4-amino-2-chloronicotinic acid

CAS: 1018678-38-0

Ref. 3D-TQB67838

Produktinformation

• Name: 4-amino-2-chloronicotinic acid
• Synonyme: 3-Pyridinecarboxylic acid, 4-amino-2-chloro-, 2-Chloro-4-aminonicotinic acid, 4-Amino-2-chloro-3-pyridinecarboxylic acid

Beschreibung

4-Amino-2-chloronicotinic acid is a nitrogenous organic compound. It is a synthetic molecule that can be used as a substrate for the chemical reactions of pyrimidine compounds, such as nucleosides and nucleotides, and it has been used as a lead structure in the design of drugs that inhibit tyrosine kinase. The synthesis of this compound involves the reaction of 4-aminoquinoline with chloroacetic acid. This synthetic process has been optimized to produce high yields and purity levels. The calcium-sensing receptor (CaSR) is an important regulator of parathyroid function, which in turn regulates calcium homeostasis in the body. A number of heterocycles have been synthesized and tested as CaSR inhibitors, with 4-amino-2-chloronicotinic acid being one of them. In vitro studies have shown that this compound inhibits CaSR activity at picomolar concentrations.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 172.57 g/mol
• Formel: C₆H₅ClN₂O₂
• Reinheit: Min. 95%