2-Phenyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid

CAS: 19983-15-4

Ref. 3D-UAA98315

Produktinformation

• Name: 2-Phenyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid
• Synonyme: 2-Thiazoline-4-carboxylic acid, 2-phenyl-, 4,5-Dihydro-2-phenyl-4-thiazolecarboxylic acid, 2-Phenyl-2-thiazoline-4-carboxylic acid, 4-Thiazolecarboxylic acid, 4,5-dihydro-2-phenyl-

Beschreibung

2-Phenyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid is an intermediate in the biosynthesis of flavoproteins. It is synthesized by a nonribosomal peptide synthetase (NRPS) and then converted to an active form of the enzyme by excision of the thiazole moiety. This conversion is catalyzed by a flavoprotein. The reaction proceeds via oxidative hydrogenation reactions, which are catalysed by a cytochrome P450 reductase and NADPH. 2-Phenyl-4,5-dihydro-1,3-thiazole-4 carboxylic acid has been shown to be effective in vitro as an inhibitor of bleomycin hydrolase activity and as an inhibitor of hydrogenation reactions that produce hydrogen peroxide from hydroperoxides.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 207.25 g/mol
• Formel: C₁₀H₉NO₂S
• Reinheit: Min. 95%