NSC 668036

CAS: 144678-63-7

Ref. 3D-UFA67863

Produktinformation

• Name: NSC 668036
• Synonyme: (2S)-N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanyl-2-hydroxy-3-methyl-butanoic acid
• Marke: Biosynth
• Beschreibung: NSC 668036 is a natural compound with antitumor properties. It has been shown to inhibit the growth of tumor cells by altering cell signaling pathways. NSC 668036 blocks the signal transduction pathway of epidermal growth factor (EGF) and interferes with the activation of the downstream protein kinase, which inhibits the phosphorylation and inactivation of glycogen synthase kinase-3β (GSK-3β). This leads to a decrease in intracellular calcium levels, which has been shown to be associated with chemoresistance. In vitro studies have confirmed that NSC 668036 suppresses proliferation of colorectal cancer cells and inhibits metastasis as well as increased ATP levels.

Chemische Eigenschaften

• Molekulargewicht: 460.52 g/mol
• Formel: C₂₁H₃₆N₂O₉
• Reinheit: Min. 95%