GNE-317

CAS: 1394076-92-6

Ref. 3D-UFC07692

Produktinformation

• Name: GNE-317
• CAS: 1394076-92-6

Beschreibung

GNE-317 is a cancer therapeutic that inhibits the activity of CDK4/6 and is currently in phase II clinical trials. GNE-317 has been shown to be effective in inhibiting tumor growth in mice with metastatic melanoma. The mechanism of action of GNE-317 is by binding to CDK4/6 and inhibiting their activity, which prevents phosphorylation of effector proteins such as S6 kinase. This inhibition leads to a decrease in cell proliferation and an increase in apoptosis.
GNE-317 has been shown to inhibit the growth of human breast cancer cells without affecting normal cells. It also inhibits Hdac, a protein involved in cell signaling pathways that can lead to uncontrolled cell growth, which may be due to its ability to inhibit histone deacetylation.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 414.48 g/mol
• Formel: C₁₉H₂₂N₆O₃S
• Reinheit: Min. 95%