CRAC inhibitor 44

CAS: 944917-72-0

Ref. 3D-UMB91772

Produktinformation

• Name: CRAC inhibitor 44
• Marke: Biosynth
• Beschreibung: CRAC inhibitor 44 is a guanine nucleotide-binding protein that inhibits the activity of ABCG2, which is an important drug transporter in the blood-brain barrier. CRAC inhibitor 44 binds to the ABCG2 transporter and prevents it from transporting drugs across the blood-brain barrier. This inhibition leads to neuronal death and has been shown to be effective against oxidative injury. The binding of CRAC inhibitor 44 to ABCG2 also inhibits calcium binding and autophagy, which are important processes in cell survival. In vitro experiments using a polymerase chain reaction (PCR) system on human cells have shown that CRAC inhibitor 44 can inhibit transcriptional regulation by preventing mRNA production. Histological analysis of mice treated with CRAC inhibitor 44 showed that this drug led to brain damage due to its ability to inhibit DNA repair enzymes, such as polymerase chain reaction (PCR) activity and transcriptional regulation.

Chemische Eigenschaften

• Molekulargewicht: 475.6 g/mol
• Formel: C₂₆H₄₁N₃O₅
• Reinheit: Min. 95%