Doxazosin-d8 hydrochloride

CAS: 1219803-95-8

Ref. 3D-UYB80395

Produktinformation

• Name: Doxazosin-d8 hydrochloride
• Marke: Biosynth
• Beschreibung: Doxazosin-d8 hydrochloride is an analytical reference standard for HPLC and LCMS, and a drug development impurity. It is a metabolite of doxazosin that is used as an impurity in the manufacture of doxazosin. Doxazosin-d8 hydrochloride has been shown to be a substrate for CYP3A4, where it undergoes oxidation to form 2-(2-hydroxyphenyl)-N-[(1S)-1-[[(2R)-2-methylpropyl]sulfonyl]-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-(2,6 dimethylphenyl)acetamide (CYP3A4). This metabolite may contribute to the pharmacological activity of doxazosin.

Chemische Eigenschaften

• Molekulargewicht: 495.99 g/mol
• Formel: C₂₃H₁₈D₈ClN₅O₅
• Reinheit: Min. 95%