hBID peptide

Ref. 3D-VAC-00945

Produktinformation

• Name: hBID peptide
• Synonyme: Ac-WEDIIRNIARHLAQVGDSMDR-NH2 TFA salt
• Marke: Biosynth
• Beschreibung: BH3 interacting-domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family. BID is a BH3-only protein that connects the extrinsic TNFR1 and Fas death signaling pathway to the mitochondrial amplification cascade of the intrinsic death pathway. BID is believed to activate multidomain pro-apoptotic proteins BAX or BAK directly. hBID peptide is a 21 amino acid amide from the human protein BID. BID is BH3-interacting domain death agonist. This hBID peptide encompasses the BH3 motif containing the conserved LXXXXD, which is required for BID for pro-apoptotic activity and to interact with anti-apoptotic members of the Bcl-2 family. It is a useful reagent for BH3 profiling,