Lucidenic acid B

CAS: 95311-95-8

Ref. 3D-VDA31195

Produktinformation

• Name: Lucidenic acid B
• Synonyme: (+)-Lucidenic acid B, (5α,7β,12β)-7,12-Dihydroxy-4,4,14-trimethyl-3,11,15-trioxochol-8-en-24-oic acid, Chol-8-en-24-oic acid, 7,12-dihydroxy-4,4,14-trimethyl-3,11,15-trioxo-, (5α,7β,12β)-

Beschreibung

Lucidenic acid B is a molecule that has been shown to have cytotoxic effects on human HL-60 cells. It also has the ability to reduce the glomerular filtration rate, which may be due to its ability to inhibit the synthesis of growth factors and mitochondrial membrane potential. Lucidenic acid B also inhibits cancer cell proliferation, as it induces apoptosis. In addition, this molecule has been shown to inhibit cyclooxygenase-2 (COX-2) activity, which leads to an inhibition of prostaglandin synthesis and subsequent prostaglandin-mediated inflammation. Lucidenic acid B also specifically binds to NF-κB DNA binding sites and inhibits nuclear translocation of NF-κB subunits p65 and p50.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 474.59 g/mol
• Formel: C₂₇H₃₈O₇
• Reinheit: Min. 95%