BIIB-057

CAS: 1370261-96-3

Ref. 3D-VEC26196

Produktinformation

• Name: BIIB-057
• Synonyme: 2-[[(1R,2S)-2-Aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide
• CAS: 1370261-96-3

Beschreibung

BIIB-057 is a monoclonal antibody that binds to the 2-adrenergic receptor and blocks the signal transduction of the inflammatory response. BIIB-057 has been shown to inhibit the activation of primary cells from patients with bowel disease, and to have a clinical relevance in treating inflammatory bowel disease. BIIB-057 inhibits the pro-apoptotic protein, AIF, which is responsible for apoptosis in cancer cells. This drug also blocks cell signaling pathways, such as Toll-like receptor 4 (TLR4) and TLR9, found on endothelial cells and macrophages. BIIB-057 is an immunoglobulin G1 kappa humanized monoclonal antibody that targets PD-L1 and PD-L2.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 393.45 g/mol
• Formel: C₁₉H₂₃N₉O
• Reinheit: Min. 95%