BMS 214662

CAS: 195987-41-8

Ref. 3D-VHA98741

Produktinformation

• Name: BMS 214662
• Synonyme: 7-cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine, Bms 214662, (3R)-3-benzyl-1-(1H-imidazol-5-ylmethyl)-4-(thiophen-2-ylsulfonyl)-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-7-carbonitrile
• CAS: 195987-41-8

Beschreibung

BMS 214662 is a potent, selective, and orally available inhibitor of the BCR-ABL kinase. It has been shown to inhibit the activity of this enzyme in vitro and in vivo. The BCR-ABL kinase plays a central role in the molecular pathogenesis of chronic myeloid leukemia (CML), affecting cellular proliferation, differentiation, apoptosis, and cell signaling pathways. Inhibition of this enzyme by BMS 214662 may lead to tumor regression.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 489.61 g/mol
• Formel: C₂₅H₂₃N₅O₂S₂
• Reinheit: Min. 95%