7α,24(S)-Dihydroxycholesterol

CAS: 245523-67-5

Ref. 3D-VJA52367

Produktinformation

• Name: 7α,24(S)-Dihydroxycholesterol
• Marke: Biosynth
• Beschreibung: 7α,24(S)-Dihydroxycholesterol (7α,24(S)-DHCH) is a fatty acid that is produced by the liver and is an intermediate in cholesterol biosynthesis. 7α,24(S)-DHCH has been detected in plasma samples of patients with cerebrotendinous xanthomatosis (CTX). It has also been found to be elevated in tuberculosis patients with carotid involvement. The levels of 7α,24(S)-DHCH were found to be higher than those of other oxysterols in CTX patients. In order to identify the origin of this molecule, a LC-MS/MS method was developed for the detection and quantification of 7α,24(S)-DHCH. This method uses chemical ionization for mass spectrometric analysis and can detect 7α,24(S)-DHCH at concentrations as low as 1 ng/mL. Histological analyses were conducted on human tissue samples

Chemische Eigenschaften

• Molekulargewicht: 418.65 g/mol
• Formel: C₂₇H₄₆O₃
• Reinheit: Min. 95%