LCH-7749944

CAS: 796888-12-5

Ref. 3D-WGB88812

Produktinformation

• Name: LCH-7749944
• CAS: 796888-12-5

Beschreibung

LCH-7749944 is a potent inhibitor of the kinase activity of β-catenin. It binds to the ATP binding site and blocks the ATP-dependent phosphorylation of β-catenin, which inhibits its ability to translocate into the nucleus and function as a transcription factor. LCH-7749944 has shown efficacy in preclinical models for cancer and inflammatory diseases. The drug was shown to inhibit the growth of human fibroblasts in culture, leading to cell death. LCH-7749944 also showed an inhibitory effect on epidermal growth factor receptor (EGFR) signaling pathways that have been implicated in many cancers.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 350.4 g/mol
• Formel: C₂₀H₂₂N₄O₂
• Reinheit: Min. 95%