PI-103

CAS: 371935-74-9

Ref. 3D-WPA93574

Produktinformation

• Name: PI-103
• Synonyme: 3-[4-(4-Morpholinyl)pyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-2-yl]phenol, 3-[4-(4-Morpholinylpyrido)[3',2':4,5]Furo[3,2-D]Pyrimidin-2-Yl]Phenol Hydrochloride, Phenol, 3-[4-(4-morpholinyl)pyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-2-yl]-, Pi 103, Pik 103, 3-(4-Morpholinopyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-2-yl)phenol

Beschreibung

PI-103 is a potent inducer of apoptosis. It has low potency and is selective for solid tumours, such as breast cancer. PI-103 inhibits the mitochondrial membrane potential by binding to the voltage-dependent anion channel (VDAC) in the outer mitochondrial membrane. PI-103 also inhibits protein synthesis and induces cell death by activating caspase 9 and caspase 3. PI-103 is also used to treat viral infections, such as hepatitis C virus, and bacterial infections, including tuberculosis.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 348.36 g/mol
• Formel: C₁₉H₁₆N₄O₃
• Reinheit: Min. 95%
• Farbe/Form: Powder