Produktinformation
- 2-Allosecurinine(8CI)
- Phyllochrysine (6CI,7CI)
- Securinan-11-one, (2a)-
- (-)-Allosecurinine
- (-)-Phyllochrysine
- Nsc 107415
Allosecurinin is a natural compound that is produced by the fungus Allosclerotium rostratum. It has been shown to inhibit the ATP-binding cassette transporter in HL-60 cells, which is necessary for the production of new DNA. This compound has also been shown to have significant cytotoxicity against human cancer cells and to possess anti-inflammatory properties. Allosecurinin demonstrates antiviral activity against HIV and herpes simplex virus type 1 (HSV-1) in vitro as well as potent cytotoxicity against k562 leukemia cells. Allosecurinin also has demonstrated synergistic effects with other compounds, such as virosecurines, which are known for their antiviral activities. The molecular docking analysis of allosecurinine and virosecurines revealed that they may bind to different sites on the pyrimidine ring of the nucleotide ATP, which suggests that these two compounds may act synergistically to inhibit viral replication.
Chemische Eigenschaften
Technische Anfrage zu: 3D-XA176463 Allosecurinin
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