Exostemin

CAS: 16281-62-2

Ref. 3D-XE163788

Produktinformation

• Name: Exostemin
• Synonyme: Coumarin,8-hydroxy-5,7-dimethoxy-4-(p-methoxyphenyl)- (8CI)

Beschreibung

Exostemin is a rubiaceae plant extract that has been shown to have significant cytotoxic effects against human leukemia cells. It also inhibits the growth of epidermoid carcinomas in mice. Exostemin is a neoflavanoid, which are compounds that are structurally related to flavanoids. The chemical structures of these compounds can be found in the skeleton shown above. Exostemin induces apoptosis and necrosis in cancer cells through a mechanism that is not yet fully understood, but may involve inhibition of protein synthesis at the ribosome level.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 328.32 g/mol
• Formel: C₁₈H₁₆O₆
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C18H16O6/c1-21-11-6-4-10(5-7-11)12-8-15(19)24-18-16(12)13(22-2)9-14(23-3)17(18)20/h4-9,20H,1-3H3
• InChI Key: InChIKey=NBXASEHAOQMXCJ-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2cc(=O)oc3c(O)c(OC)cc(OC)c23)cc1