Sulukast

CAS: 98116-53-1

Ref. 3D-YDA11653

Produktinformation

• Name: Sulukast
• Synonyme: Sulukast [USAN:INN], Ly 170680, 3-(((1R,2E,4Z)-1-((alphaS)-alpha-Hydroxy-m-1H-tetrazol-5-ylbenzyl)-2,4-tetradecadienyl)thio)propionic acid, Propanoic acid, 3-((1-(hydroxy(3-(1H-tetrazol-5-yl)phenyl)methyl)-2,4-tetradecadienyl)thio)-, (R-(R*,S*-(E,Z)))-, Sulukastum, Sulukastum [INN-Latin], Unii-M652A5186T, 3-{[(1R,2E,4Z)-1-{(S)-hydroxy[3-(2H-tetrazol-5-yl)phenyl]methyl}tetradeca-2,4-dien-1-yl]sulfanyl}propanoic acid

Beschreibung

Sulukast is a leukotriene receptor antagonist that blocks leukotriene-induced bronchoconstriction. It is used in the treatment of asthma and chronic obstructive pulmonary disease. Sulukast binds to two types of receptors, the cysteinyl leukotriene receptor 1 (CysLT1) and the cysteinyl leukotriene receptor 2 (CysLT2). The binding activates adenyl cyclase, which leads to increased levels of cyclic AMP. This increase in cyclic AMP causes an increase in calcium influx into cells and activation of protein kinase A, resulting in phosphorylation and deactivation of CysLT1s. Sulukast also inhibits the binding of peptides to receptors on cells, which may be useful for research purposes.
*Sulukast is a high-purity ligand with a purity greater than 99%. It has a molecular weight

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 472.60 g/mol
• Formel: C₂₅H₃₆N₄O₃S
• Reinheit: Min. 95%