Ofloxacin d3 hydrochloride

CAS: 1173021-78-7

Ref. 3D-YWB02178

Produktinformation

• Name: Ofloxacin d3 hydrochloride
• Marke: Biosynth
• Beschreibung: Ofloxacin d3 hydrochloride is a deuterated form of the quinolone antibiotic, which is a synthetic derivative designed for research purposes. It is sourced from the fluorinated carboxyquinolone class, where deuterium atoms replace certain hydrogen atoms to study metabolic pathways involving ofloxacin with minimal isotopic interference. Ofloxacin d3 inhibits bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication, transcription, and repair. By stabilizing the transient cleavable complex with DNA, it prevents the ligation of DNA strands, leading to bacterial cell death. This compound is utilized primarily in laboratory settings for studying the pharmacokinetics and biodistribution of quinolones, as well as for elucidating resistance mechanisms in bacterial strains. Its stable isotopic composition makes it ideal for advanced analytical techniques such as mass spectrometry. Through these investigations, insights into drug metabolism, efficacy, and resistance can be gleaned, contributing to the broader understanding of quinolone antibiotic activity.

Chemische Eigenschaften

• Molekulargewicht: 400.8 g/mol
• Formel: C₁₈H₂₁ClFN₃O₄
• Reinheit: Min. 95%