Produktinformation
- 1,1-DICHLOROSILACYCLOBUTANE
- 1,1-Dichloro-1-silacyclobutane
- 1,1-Dichlorosiletane
- Cyclotrimethylenedichlorosilane
- Silacyclobutane, 1,1-dichloro-
Silane Cross-Coupling Agent
The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.
Cyclotrimethylenedichlorosilane; 1,1-Dichlorosilacyclobutane
Reaction with LiN(iPr)2 and CH2X2 provides 1,1-dimethyl-2-halosilacyclopentanesArylchlorosilyl derivatives used in cross-coupling to biarylsVinylchlorosilyl derivatives used in cross-coupling to 1,3-butadienesStarting material for spirocyclic organosilanesPrecursor for aryl-substituted silacyclobutanes useful for aryl cross-coupling reactionsExtensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
