Bufogenin

CAS: 465-39-4

Ref. BP-BP0289

Produktinformation

• Name: Bufogenin
• Synonyme: Resibufogenin, Respigon, (3Beta,5Beta,15Beta)-3-Hydroxy-14,15-Epoxybufa-20,22-Dienolide, (3Beta,5Beta,8Xi,9Xi,15Beta)-3-Hydroxy-14,15-Epoxybufa-20,22-Dienolide, (3β,5β,15β)-14,15-Epoxy-3-hydroxybufa-20,22-dienolide, 14,15β-Epoxy-3β-hydroxy-5β-bufa-20,22-dienolide, 3-Hydroxy-14,15-Epoxybufa-20,22-Dienolide, 3β-Hydroxy-14,15β-epoxy-5β-bufa-20,22-dienolide, 5β-Bufa-20,22-dienolide, 14,15β-epoxy-3β-hydroxy-, Bufa-20,22-dienolide, 14,15-epoxy-3-hydroxy-, (3β,5β,15β)-, NSC 90783, Recibufogenin, Resinobufagin

Beschreibung

Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu, which exhibits the anti-proliferative effect against cancer cells through the degradation of cyclin D1 caused by the activation of GSK-3β. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction.

• Marke: Biopurify

Chemische Eigenschaften

• Molekulargewicht: 384.516
• Formel: C₂₄H₃₂O₄
• Reinheit: 95%~99%