calycosin-7-O-β-D-glucoside

CAS: 20633-67-4

Ref. BP-BP0306

Produktinformation

• Name: calycosin-7-O-β-D-glucoside
• Synonyme: Calycosin 7-glucoside, 3-(3-Hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside, 4H-1-benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-3-(3-hydroxy-4-methoxyphenyl)-, Calycosin-O-Glucopyranoside, Calycosin 7-O-Glucoside, Calycosin 7-O-β-D-glucopyranoside

Beschreibung

Calycosin-7-O-β-d-glucoside(CG) treatment can significantly reduce infarct volume, histological damage and BBB permeability in the in vivo MCAO ischemia-reperfusion rat model; inhibit the expression and activities of MMPs, and secure the expression of cav-1 and tight junction proteins in the microvessels isolated from ischemic rat cortex; scavenge NO, inhibit the activities of MMP-2 and MMP-9, and attenuate cell death in the in vitro cultured brain microvascular endothelial cells under OGD condition; thus CG could protect BBB integrity in experimental cerebral ischemia-reperfusion injury via regulating NO/cav-1/MMPs pathway.

• Marke: Biopurify

Chemische Eigenschaften

• Molekulargewicht: 446.408
• Formel: C₂₂H₂₂O₁₀
• Reinheit: 95%~99%
• Farbe/Form: Powder