Carnosol

CAS: 5957-80-2

Ref. BP-BP0317

Produktinformation

• Name: Carnosol
• Synonyme: Picrosalvin, (4aR,9S,10aS)-1,3,4,9,10,10a-Hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-2H-9,4a-(epoxymethano)phenanthren-12-one, (5Beta)-11,12-Dihydroxy-7,20-Epoxyabieta-8(14),9(11),12-Trien-20-One, (5Beta,7Alpha)-11,12-Dihydroxy-7,20-Epoxyabieta-8,11,13-Trien-20-One, (5Xi)-11,12-Dihydroxy-7,20-Epoxyabieta-8(14),9(11),12-Trien-20-One, 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10aS)-, 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR-(4aalpha,9alpha,10abeta))-, 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, [4aR-(4aα,9α,10aβ)]-, Ccris 7122, Hsdb 7680, NSC 39143, Podocarpa-8,11,13-trien-17-oic acid, 7β,11,12-trihydroxy-13-isopropyl-, 17,7-lactone

Beschreibung

Carnosol, a novel agonist of TRPA1 with an EC50 value of 12.46 uM, which exhibits anti-inflammatory, anti-nociceptive, hepatoprotective, antioxidant, anticarcinogen, anti-angiogenic, anti- invasive and antimetastatic properties. Carnosol can cause a significant decrease in both bacterial and yeast growth whilst, it may prove useful as a food antioxidant which could also contribute to the retardation of the microbial spoilage of foods; it also can inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase2 enzymes and activation of glutathione metabolism, it may be a potential drug against obesity-related diseases.

• Marke: Biopurify

Chemische Eigenschaften

• Molekulargewicht: 330.424
• Formel: C₂₀H₂₆O₄
• Reinheit: 95%~99%