Loureirin B

CAS: 119425-90-0

Ref. BP-BP0885

Produktinformation

• Name: Loureirin B
• Synonyme: 1-(4-Hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-1-propanone, 1-(4-Hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)propan-1-one, 1-Propanone, 1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-, 4′-Hydroxy-2,4,6-trimethoxydihydrochalcone, Lr-B, Propan-1-one, 1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-

Beschreibung

Loureirin B, a flavonoid extracted from Dracaena cochinchinensis, is an inhibitor of plasminogen activator inhibitor-1 (PAI-1), with an IC50 of 26.10 μM; Loureirin B also inhibits KATP, the phosphorylation of ERK and JNK, and has anti-diabetic activity.Loureirin B inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via TGF-β/Smad pathway, loureirin B can suppress tetrodotoxin-sensitive (TTX-S) voltage-gated sodium currents in a dose-dependent way.

• Marke: Biopurify

Chemische Eigenschaften

• Molekulargewicht: 316.353
• Formel: C₁₈H₂₀O₅
• Reinheit: 95%~99%
• InChl: InChI=1S/C18H20O5/c1-21-14-10-17(22-2)15(18(11-14)23-3)8-9-16(20)12-4-6-13(19)7-5-12/h4-7,10-11,19H,8-9H2,1-3H3
• InChI Key: InChIKey=ZPFRAPVRYLGYEC-UHFFFAOYSA-N
• SMILES: COc1cc(OC)c(CCC(=O)c2ccc(O)cc2)c(OC)c1