Vicenin II

CAS: 23666-13-9

Ref. BP-BP1605

Produktinformation

• Name: Vicenin II
• Synonyme: 6,8-Di-C-glucopyranosylapigenin, 6,8-Di-C-glucosylapigenin, 4H-1-Benzopyran-4-one, 6,8-di-β-<span class="text-smallcaps">D</span>-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6,8-bis[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-bis[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-4H-chromen-4-one (non-preferred name), 5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-bis[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-4H-chromen-4-one (non-preferred name), 6,8-Di-C-β-<span class="text-smallcaps">D</span>-glucopyranosylapigenin, 6,8-Di-C-β-glucosylapigenin, 6,8-Di-β-<span class="text-smallcaps">D</span>-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Apigenin 6,8-C-di-β-<span class="text-smallcaps">D</span>-glucopyranoside, Apigenin 6,8-bis(C-β-<span class="text-smallcaps">D</span>-glucopyranoside), Apigenin 6,8-di-C-<span class="text-smallcaps">D</span>-glucoside, Apigenin 6,8-di-C-glucopyranoside, Apigenin 6,8-di-C-glucoside, Apigenin 6,8-di-C-β-<span class="text-smallcaps">D</span>-glucoside, Apigenin 6,8-di-glucopyranoside, Vicenin, Violantin

Beschreibung

Vicenin-2 (VCN-2), an active constituent of the medicinal herb Ocimum Sanctum Linn or Tulsi, it can effectively induce anti-proliferative, anti-angiogenic and pro-apoptotic effect in CaP cells (PC-3, DU-145 and LNCaP) irrespective of their androgen responsiveness or p53 status;VCN-2 in combination with docetaxel (DTL) synergistically inhibited the growth of prostate tumors in vivo with a greater decrease in the levels of AR, pIGF1R, pAkt, PCNA, cyclin D1, Ki67, CD31, and increase in E-cadherin; it could as a single agent and in combination with DTL in carcinoma of prostate (CaP).

• Marke: Biopurify

Chemische Eigenschaften

• Molekulargewicht: 594.522
• Formel: C₂₇H₃₀O₁₅
• Reinheit: 95%~99%
• Farbe/Form: Yellow powder