Soyasaponin Ab

CAS: 118194-13-1

Ref. BP-BP1735

Produktinformation

• Name: Soyasaponin Ab
• Synonyme: Acetylsoyasaponin A1, (3β,4β,21β,22β)-21,23-Dihydroxy-22-[[3-O-(2,3,4,6-tetra-O-acetyl-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl)-α-<smallcap>L</smallcap>-arabinopyranosyl]oxy]olean-12-en-3-yl O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→2)-O-β-<smallcap>D</smallcap>-galactopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranosiduronic acid, SoyasaponinAb, β-<span class="text-smallcaps">D</smallcap>-Glucopyranosiduronic acid, (3β,4β,21β,22β)-21,23-dihydroxy-22-[[3-O-(2,3,4,6-tetra-O-acetyl-β-<smallcap>D</smallcap>-glucopyranosyl)-α-<smallcap>L</smallcap>-arabinopyranosyl]oxy]olean-12-en-3-yl O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→2)-O-β-<smallcap>D</span>-galactopyranosyl-(1→2)-

Beschreibung

Soyasaponin Ab may represent a viable candidate for effective vaccine adjuvant, TLR4 receptor dependent pathway may be involved in immune stimulatory effects of soyasaponin Ab. Soyasaponin Ab has anti-inflammatory effects, it can inhibit colon shortening, myeloperoxidase activity, the expression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), and activation of the transcription factor nuclear factor-κB (NF-κB); soyasaponin Ab (1, 2, 5, and 10 μM) can inhibit the production of NO (IC50 = 1.6 ± 0.1 uM) and prosta. Soyasaponin Aa and Ab can markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes through the downregulation of the adipogenesis-related transcription factors PPARγ and C/EBPα in 3T3-L1 adipocytes. They also can prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase, exhibit memory-enhancing effects.

• Marke: Biopurify

Chemische Eigenschaften

• Molekulargewicht: 1437.54
• Formel: C₆₇H₁₀₄O₃₃
• Reinheit: 95%~99%
• Farbe/Form: Powder