P63-α (3F11) Mouse mAb

Ref. EK-EM1404

Produktinformation

• Name: P63-α (3F11) Mouse mAb

Beschreibung

p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .

• Marke: ELK Biotechnology