Stat4 (phospho Tyr693) rabbit pAb

Ref. EK-ES1407

Produktinformation

• Name: Stat4 (phospho Tyr693) rabbit pAb
• Synonyme: STAT4; Signal transducer and activator of transcription 4

Beschreibung

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],

• Marke: ELK Biotechnology