CHP2 rabbit pAb

Ref. EK-ES1979

Produktinformation

• Name: CHP2 rabbit pAb
• Synonyme: CHP2; HCA520; Calcineurin B homologous protein 2; Hepatocellular carcinoma-associated antigen 520
• Marke: ELK Biotechnology
• Beschreibung: This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520. [provided by RefSeq, Jul 2013],