c-Myb (Acetyl Lys471) rabbit pAb

Ref. EK-ES20114

Produktinformation

• Name: c-Myb (Acetyl Lys471) rabbit pAb
• Synonyme: Transcriptional activator Myb (Proto-oncogene c-Myb)

Beschreibung

domain:Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.,function:Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.,PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.,

• Marke: ELK Biotechnology