DNA pol β (Acetyl Lys72) rabbit pAb

Ref. EK-ES20123

Produktinformation

• Name: DNA pol β (Acetyl Lys72) rabbit pAb
• Synonyme: DNA polymerase beta (EC 2.7.7.7;EC 4.2.99.-)

Beschreibung

catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Binds 2 magnesium ions per subunit.,domain:Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.,function:Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.,PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.,similarity:Belongs to the DNA polymerase type-X family.,subunit:Monomer.,

• Marke: ELK Biotechnology