Pdcd-1 rabbit pAb

Ref. EK-ES20278

Produktinformation

• Name: Pdcd-1 rabbit pAb
• Synonyme: Programmed cell death protein 1 (Protein PD-1;hPD-1;CD antigen CD279)

Beschreibung

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008],

• Marke: ELK Biotechnology