XRCC1 rabbit pAb

Ref. EK-ES3713

Produktinformation

• Name: XRCC1 rabbit pAb
• Synonyme: XRCC1; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1

Beschreibung

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],

• Marke: ELK Biotechnology