ZnT-8 rabbit pAb

Ref. EK-ES4993

Produktinformation

• Name: ZnT-8 rabbit pAb
• Synonyme: SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8

Beschreibung

The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],

• Marke: ELK Biotechnology