Dok-7 rabbit pAb

Ref. EK-ES5609

Produktinformation

• Name: Dok-7 rabbit pAb
• Synonyme: DOK7; C4orf25; Protein Dok-7; Downstream of tyrosine kinase 7
• Marke: ELK Biotechnology
• Beschreibung: docking protein 7(DOK7) Homo sapiens The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],