Cadherin-23 rabbit pAb

Ref. EK-ES7147

Produktinformation

• Name: Cadherin-23 rabbit pAb
• Synonyme: CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin

Beschreibung

This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013],

• Marke: ELK Biotechnology