Stat2 (phospho Tyr631) rabbit pAb
Ref. EK-ES7295
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Produktinformation
- STAT2; Signal transducer and activator of transcription 2; p113
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
Chemische Eigenschaften
Technische Anfrage zu: EK-ES7295 Stat2 (phospho Tyr631) rabbit pAb
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