ASCL1 rabbit pAb

Ref. EK-ES8645

Produktinformation

• Name: ASCL1 rabbit pAb
• Synonyme: Achaete-scute homolog 1 (ASH-1;hASH1;Class A basic helix-loop-helix protein 46;bHLHa46)

Beschreibung

achaete-scute family bHLH transcription factor 1(ASCL1) Homo sapiens This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008],

• Marke: ELK Biotechnology