Samuraciclib hydrochloride

CAS: 1805789-54-1

Ref. TM-T10898

Produktinformation

• Name: Samuraciclib hydrochloride
• Synonyme: ICEC0942 hydrochloride, CT7001 hydrochloride
• CAS: 1805789-54-1

Beschreibung

Samuraciclib hydrochloride (ICEC0942 hydrochloride) is a potent, selective, ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45-, 15-, 230- and 30-fold higher than CDK1, CDK2 (IC50 is 578 nM), CDK5 and CDK9 respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 μM. Samuraciclib hydrochloride has anti-tumor effects.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 430.97
• Formel: C₂₂H₃₁ClN₆O
• Reinheit: 99.57%
• Farbe/Form: Solid