Rofecoxib

CAS: 162011-90-7

Ref. TM-T1185

Produktinformation

• Name: Rofecoxib
• Synonyme: MK 966, MK-0966, 2(5H)-Furanone, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-, 3-(4-Methanesulfonylphenyl)-2-phenyl-2-buten-4-olide, 3-Phenyl-4-[4-(Methylsulfonyl)phenyl]-2(5H)-furanone, 4-(4-(Methanesulfonyl)phenyl)-3-phenyl-5H-furan-2-one, 4-[4-(Methylsulfonyl)-phenyl]-3-phenyl-2(5H)-furanone, 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one, Ceeoxx, Ceoxx, Mk 0966, Mk 966, Rhuma-cure, Romacox, Vioxx
• CAS: 162011-90-7

Beschreibung

Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyretic and analgesic properties and potential antineoplastic properties. COX-related metabolic pathways may represent key regulators of cell proliferation and neo-angiogenesis. Some epithelial tumor cell types overexpress pro-angiogenic COX-2.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 314.36
• Formel: C₁₇H₁₄O₄S
• Reinheit: 99.94%
• Farbe/Form: Off-White (Pale Yellow) Crystalline Powder