PXS-5153A monohydrochloride

CAS: 2125956-82-1

Ref. TM-T12585L

Produktinformation

• Name: PXS-5153A monohydrochloride
• Synonyme: PXS-5153A monohydrochloride (2125956-82-1 free base)
• CAS: 2125956-82-1

Beschreibung

PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC 50 of <40 nM for LOXL2 across all mammalian species and an IC 50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride dose-dependently reduced LOXL2-mediated collagen oxidation and collagen crosslinking in vitro which may represent an innovative therapeutic approach for the treatment of fibrosis

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 475.41
• Formel: C₂₀H₂₅Cl₂FN₄O₂S
• Reinheit: 98%
• Farbe/Form: Solid