SB-657510

CAS: 474960-44-6

Ref. TM-T12848

Produktinformation

• Name: SB-657510
• CAS: 474960-44-6

Beschreibung

SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively. SB-657510 plays an anti-inflammatory role by inhibiting UII-induced inflammatory mediators, such as adhesion molecules, in human vascular endothelial cells and upregulation of cytokines and tissue factors. SB 657510 has a therapeutic effect on diabetes-related atherosclerotic disease in diabetic mouse models.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 505.81
• Formel: C₁₉H₂₂BrClN₂O₅S
• Reinheit: 98.03%
• Farbe/Form: Solid