Solabegron

CAS: 252920-94-8

Ref. TM-T12970

Produktinformation

• Name: Solabegron
• Synonyme: GW 427353, (-)-(R)-3′-[[2-[[2-(3-Chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino]biphenyl-3-carboxylic acid, 3′-[[2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino][1,1′-biphenyl]-3-carboxylic acid, Gw 427353, [1,1′-Biphenyl]-3-carboxylic acid, 3′-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino]-
• CAS: 252920-94-8

Beschreibung

Solabegron (GW 427353) is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR(EC50 : 22 nM). It is used for treatment of overactive bladder and irritable bowel syndrome.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 410.89
• Formel: C₂₃H₂₃ClN₂O₃
• Reinheit: 98.99%
• Farbe/Form: Solid
• InChl: InChI=1S/C23H23ClN2O3/c24-20-8-2-6-18(13-20)22(27)15-25-10-11-26-21-9-3-5-17(14-21)16-4-1-7-19(12-16)23(28)29/h1-9,12-14,22,25-27H,10-11,15H2,(H,28,29)/t22-/m0/s1
• InChI Key: InChIKey=LLDXOPKUNJTIRF-QFIPXVFZSA-N
• SMILES: O=C(O)c1cccc(-c2cccc(NCCNC[C@H](O)c3cccc(Cl)c3)c2)c1