CU-T12-9

CAS: 1821387-73-8

Ref. TM-T15017

Produktinformation

• Name: CU-T12-9
• Synonyme: CUT129, CU-T-12-9
• CAS: 1821387-73-8

Beschreibung

CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 362.31
• Formel: C₁₇H₁₃F₃N₄O₂
• Reinheit: 99.93%
• Farbe/Form: Solid