Fenobam

CAS: 57653-26-6

Ref. TM-T15275

Produktinformation

• Name: Fenobam
• Synonyme: 1-(3-Chlorophenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)urea, 1-(3-chlorophenyl)-3-[(2E)-1-methyl-4-oxoimidazolidin-2-ylidene]urea, 57653-26-6, N-(3-Chlorophenyl)-N′-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea, Urea, N-(3-chlorophenyl)-N′-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)-, urea, N-(3-chlorophenyl)-N'-[(2E)-1-methyl-4-oxo-2-imidazolidinylidene]-
• CAS: 57653-26-6

Beschreibung

Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM). Fenobam has anxiolytic activity. Fenobam is a selective and non-competitive mGluR5 antagonist acting at an allosteric modulatory site (Kd values are 54 and 31 nM for rat and human recombinant mGlu5 receptors, respectively).

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 266.68
• Formel: C₁₁H₁₁ClN₄O₂
• Reinheit: 99.44%
• Farbe/Form: Solid
• InChl: InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18)
• InChI Key: InChIKey=DWPQODZAOSWNHB-UHFFFAOYSA-N
• SMILES: CN1CC(=O)N=C1NC(=O)Nc1cccc(Cl)c1