Naftifine hydrochloride

CAS: 65473-14-5

Ref. TM-T1543

Produktinformation

• Name: Naftifine hydrochloride
• Synonyme: Naftifungin, Naftifine HCl, Naftin, Exoderil, (E)-N-Cinnamyl-N-methyl(1-naphthylmethyl)amine hydrochloride, (E)-N-Cirmamyl-N-mcthyl(1一naphthylmethyl)amine hydrochloridc, 1-Naphthalenemethanamine, N-methyl-N-(3-phenyl-2-propenyl)-, hydrochloride, (E)-, 1-Naphthalenemethanamine, N-methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride (1:1), 1-Naphthalenemethanamine, N-methyl-N-[(2E)-3-phenyl-2-propenyl]-, hydrochloride, Aw 105-843, Exoderil, Naftifine HCl, Naftin, Sn 105-843
• CAS: 65473-14-5

Beschreibung

Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its effect is unknown, it appears to selectively inhibit the enzyme squalene 2, 3-epoxidase, thereby inhibiting the biosynthesis of sterol. This results in a decreased amount of sterols, especially ergosterol which is the primary fungal membrane sterol, and a corresponding accumulation of squalene in fungal cells. Naftifine hydrochloride (Naftifine HCl) can be fungicidal as well as fungistatic to yeasts depending on the concentration and the organisms involved.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 323.86
• Formel: C₂₁H₂₂ClN
• Reinheit: 99.84%
• Farbe/Form: Solid