Linopirdine

CAS: 105431-72-9

Ref. TM-T15758

Produktinformation

• Name: Linopirdine
• Synonyme: DuP 996, 1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one, 1-Phenyl-3,3-bis(4-pyridinylmethyl)-2-indolinone, 1-Phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one, 1-phenyl-3,3-bis(pyridin-4-ylmethyl)-1,3-dihydro-2H-indol-2-one, 2H-Indol-2-one, 1,3-dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-, Dup 996, Linopirdine [USAN:INN], Unii-I5Tb3Nz94T
• CAS: 105431-72-9

Beschreibung

Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Linopirdine is a cognitive enhancer. It acts by stimulating release of acetylcholine and other neurotransmitters.Linopirdine is a putative cognition-enhancing drug that increases acetylcholine release in rat brain tissue.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 391.46
• Formel: C₂₆H₂₁N₃O
• Reinheit: 99.92%
• Farbe/Form: Solid
• InChl: InChI=1S/C26H21N3O/c30-25-26(18-20-10-14-27-15-11-20,19-21-12-16-28-17-13-21)23-8-4-5-9-24(23)29(25)22-6-2-1-3-7-22/h1-17H,18-19H2
• InChI Key: InChIKey=YEJCDKJIEMIWRQ-UHFFFAOYSA-N
• SMILES: O=C1N(c2ccccc2)c2ccccc2C1(Cc1ccncc1)Cc1ccncc1