Doxifluridine

CAS: 3094-09-5

Ref. TM-T1600

Produktinformation

• Name: Doxifluridine
• Synonyme: Ro 21-9738, AMC 0101, 5'-DFUR, 5-Fluoro-5'-deoxyuridine, (2Xi)-5'-Deoxy-5-Fluorouridine, 5'-Deoxy-5-fluorouridine, 5'-Dfur, 5-Fluoro-5'-deoxyuridine, 5-Fluorodesoxyuridine, 5′-dFUrd, Flutron, Fulturon, Furtulon, Ro 21-9738, Uridine, 5′-deoxy-5-fluoro-
• CAS: 3094-09-5

Beschreibung

Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by dihydropyrimidine dehydrogenase in the gut wall, is converted into 5-FU in the presence of pyrimidine nucleoside phosphorylase. 5-FU interferes with DNA synthesis and subsequent cell division by reducing normal thymidine production and interferes with RNA transcription by competing with uridine triphosphate for incorporation into the RNA strand.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 246.19
• Formel: C₉H₁₁FN₂O₅
• Reinheit: 99.96%
• Farbe/Form: White Solid