K-Ras ligand-Linker Conjugate 5

CAS: 2378261-85-7

Ref. TM-T18058

Produktinformation

• Name: K-Ras ligand-Linker Conjugate 5
• CAS: 2378261-85-7

Beschreibung

K-Ras ligand-Linker Conjugate 5 is a chemical compound that combines a ligand for the K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The K-Ras ligand-Linker Conjugate 5 plays a crucial role in the synthesis of PROTAC K-Ras Degrader-1, a highly potent K-Ras degrader. In SW1573 cells, this degrader exhibits an impressive degradation efficacy of ≥70% [1].

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 789.96
• Formel: C₄₂H₅₉N₇O₈
• Reinheit: 98%