EGFR-IN-144

Ref. TM-T204605

Produktinformation

• Name: EGFR-IN-144
• Marke: Targetmol
• Beschreibung: EGFR-IN-144 (Compound 4B) inhibits EGFR (IC50=0.639 µg/mL) and tubulin polymerization (IC50=7.339 µg/mL). It exhibits cytotoxicity in various cancer cells with a GI50 at the nanomolar level. EGFR-IN-144 reduces the expression of mTOR, TNF-α, and IL-6, causes G1/S phase cell cycle arrest, and induces apoptosis.

Chemische Eigenschaften

• Molekulargewicht: 418.273
• Formel: C₂₀H₁₇Cl₂N₃O₃
• Farbe/Form: Solid