CDK4/6/HDAC-IN-1

Ref. TM-T204833

Produktinformation

• Name: CDK4/6/HDAC-IN-1
• Marke: Targetmol
• Beschreibung: CDK4/6/HDAC-IN-1 (Compound N14) is a dual-target inhibitor of CDK4/6 and HDAC, with IC50 values of 7.23 nM for CDK4, 13.20 nM for CDK6, 55.66 nM for HDAC1, and 48.38 nM for HDAC6. It induces apoptosis and G0/G1 phase arrest through the HDAC-p21-CDK signaling pathway and can inhibit hepatocellular carcinoma.

Chemische Eigenschaften

• Molekulargewicht: 665.742
• Formel: C₃₅H₃₉N₉O₅
• Farbe/Form: Solid