Antitumor agent-170

Ref. TM-T210287

Produktinformation

• Name: Antitumor agent-170
• Marke: Targetmol
• Beschreibung: Antitumor agent-170 (Compound C6) inhibits PD-1/PD-L1 interaction and PARP7 with IC50 values of 0.342 μM and 7.05 nM, respectively. It shows high affinity for human PD-L1, with a Ki of 9.31 nM, and can restore T cell function while increasing IFN-γ secretion. In mouse models, Antitumor agent-170 exhibits antitumor effects against melanoma and demonstrates favorable pharmacokinetic properties.

Chemische Eigenschaften

• Molekulargewicht: 1167.49204
• Formel: C₅₉H₆₉ClF₃N₁₁O₉